Samdolite Pharmaceuticals is pharmaceutical startup company focused on design and development drugs for inflammatory skin disorders.
According to the American Academy of Dermatology, 84.5 million Americans — one in four — are impacted by skin diseases. Skin diseases cost the US health care system $75 billion in medical, preventative, and prescription and non-prescription drug costs. Acne is the most common skin disease in the United States, affecting up to 50 million Americans annually.
Approximately 85 % of people between the ages of 12 and 24 experience at least minor acne.Over 25% of women and 12% of men in their 40s report having acne.
50% of women in their 20s,
33% of women in their 30s, and
25% of women in their 40s suffer from acne. Acne can affect more than your skin. Researchers have found in study after study that people with acne can also develop: depression, anxiety, low self-esteem, poor self-image, decreased quality of life, a feeling of being all alone. Although myriad acne treatments are available, current options may not be sufficient because of a lack of efficacy, limited tolerability, or burden of cost to patients. As patients become more concerned about the risks and side-effects of acne medications such as oral antibiotics and isotretinoin, other options are needed.
The paper "Innovation in acne treatment is long overdue but the treatment pipeline looks promising" was published in The Pharmaceutical Journal in 2017. At the start of this paper the author stated:
"There is no cure, and available treatments have significant drawbacks, yet there have been no novel products launched over the past 10 years — innovation is long overdue."
“For many years it’s been repurposing the same old stuff,” says Adam Friedman, a dermatologist at the George Washington University School of Medicine and Health Sciences, Washington. Unfortunately for millions acne sufferers this statement is still actual today, 7 years after this paper was published (look at current acne clinical trial landscape below).
CURRENT ACNE CLINICAL TRIAL LANDSCAPE
This is a snapshot of Phase I–IV clinical trials for primary investigational drugs with at least one industry sponsor in the acne space in
the curated Trialtrove database. There are equal proportions of clinical trials for acne across Phase I/II and Phase III/IV. Phase I/II and
Phase II/III trials are counted as Phase II and Phase III, respectively.
